Zlatý Kůň represents earliest post-OoA expansion, basal to all Eurasians. Hub persisted 15k years post-OoA before major splits. First major wave carried IUP tools, linked Ust’Ishim, Bacho Kiro, Tianyuan as East Asian-related. This IUP wave populated West and East Eurasia around 45ka then extincted in Europe. Oase1 derives from Bacho Kiro-like with extra Neanderthal admixture. UP wave after 38ka repopulated Europe with Kostenki14, Sunghir as pure West Eurasians. West Eurasians differentiated longer in Hub than East Eurasians. Siberian ancients like Yana, Mal’ta mix UP West Eurasian with prior IUP East Asian. GoyetQ116-1 mixes UP with Bacho Kiro and Tianyuan-like. Papuans sister to Tianyuan or mix East Asians with basal OoA. Bacho Kiro had recent Neanderthal introgression 4-6 generations prior. IUP wave admixed sporadically with Neanderthals. UP expansion shows no admixture with prior IUP or Neanderthals except rare cases. East-West Eurasian split ties to IUP Hub exit timing. Hub location likely North Africa or West Asia. Zlatý Kůň links to Szeletian or IUP cultures 48-43ka. Uluzzian possibly separate Hub expansion. IUP fade in Europe coincides with Neanderthal extinction.