Dataset provides 300 high-coverage genomes from 142 diverse populations. Genomes contain 5.8 million novel base pairs missing from human reference. Mutation accumulation rate accelerated 5% in non-Africans versus Africans post-divergence. Ancestors of some present-day populations split 100,000 years ago before behavioral modernity. Indigenous Australians, New Guineans, Andamanese lack ancestry from early modern human dispersal. Their ancestry matches source of other non-Africans. PSMC analysis shows genome-wide TMRCAs supporting deep splits over 100kya. D statistic reveals transition substitution skew in non-Africans versus Africans relative to chimp. San-specific selection signals identified. Non-San terminal branch shows distinct selection. Ancestral modern human branch exhibits selection. ADMIXTURE clusters match continental groups at K=5. FST higher with STRs than SNPs alone. PCA separates populations by region on STR genotypes.