Transcriptome data from Allen Human Brain Atlas covers 20,737 genes across 68 cortical regions. Mean connectivity maps from early and late trajectory mergers compared spatially to gene expression maps. Genes with significant spatial similarity exceed ±1.96 standard deviations. Early mergers link to integrating brain areas, late mergers to segregating areas. Gene Ontology shows significant cellular components for integrators and segregators (FDR q < 0.05). Integrating areas highly express neuron projection genes. Neuron projection expression correlates strongly with trajectory merger connectivity map. Neuron projection tracks evolutionary divergences from marmoset (42.6 MYA) to human (8.8 MYA). Regression analysis yields high R2 between neuron projection and primate split timeline. Segregating nodes show warmer tones in red for lower integration. Integrating nodes show blue tones for higher connectivity. Analysis uses Desikan-Killiany atlas surface transformation. Results highlight genetic basis for divergent brain functional organization.