Statistical evaluation of autosomal STR genotypes relies on allele frequencies from random human samples in databases. No agreed quality control procedure exists for STR allele frequency databases. Reliability of STR data depends on individual research groups. Centralized quality control proven essential for haploid markers like EMPOP mtDNA and YHRD Y-chromosome. STRidER is a publicly available centrally curated online allele frequency database for autosomal STRs. STRidER expands on ENFSI DNA WG STRbASE. STRidER applies software-aided likelihood-of-genotype phylogenetic and population genetic checks. STRidER compares novel data to established datasets. STRidER maintains high quality required in forensic genetics. STRidER introduces novel tools to reduce error in autosomal STR data. STRidER offers reliable STR genotype estimates. STRidER constitutes a significant improvement for the scientific community.
Comments
Be the first to comment!