STRidER delivers centralized quality control for forensic autosomal STR allele frequency databases.
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Autosomal STR genotype evaluation depends on empirical allele frequencies from population databases. No standard quality control exists for STR databases, relying on contributor responsibility. Centralized curation minimizes errors, proven in mtDNA (EMPOP) and Y-chromosome (YHRD) databases. STRidER is a public online platform for STR allele frequencies and quality control. STRidER builds on ENFSI STRbASE with haploid and autosomal checks plus new tools. Software performs likelihood-of-genotype, phylogenetic, and population genetic checks against established data. STRidER boosts reliability of STR data for forensic genetics. Databases lack agreed QC procedures despite forensic importance. Individual group errors threaten forensic accuracy. STRidER standardizes submission and validation processes. Platform enables comparison of new data to curated sets. Quality control maintains forensic standards for STR profiling. STRidER addresses gaps in autosomal STR data curation. References highlight error risks in uncured forensic databases. STRidER innovates for scientific community in forensics.

Genetics Science Technology

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