PLOS opposes US Executive Orders disrupting science for 70 years. Disruptions already impact research communities. Government restricts knowledge via topic limits, language mandates, data removal. PLOS rejects terminology changes or data removal harming accuracy. PLOS bans author removals violating credit and accountability. Editorial policies ensure peer review integrity unchanged. Diversity of expert perspectives improves science. PLOS collaborates globally for impactful research. Open science enables rigorous review and self-correction. PLOS commits to independent, open science against censorship.