The article discusses the results of studies on the introgression of archaic hominins into the genomes of modern humans, pointing to the existence of many gene flow events between different hominin species. Recent studies provide evidence of many such events, which have left genetic traces in human populations. The author analyzes the impact of introgression on human phenotypes and the changing view of human evolution. It is widely accepted that several species of man-eating animals lived in Africa at the same time as anatomically modern humans (e.g. Homo naledi [Dirks et al., 2017]). Indeed, small but significant deviations from the expected imbalance of coupling and demographic trends trigger introgression from archaic man-eaters in Africa (Durvasula and Sankararaman, 2018: Hammer et al, 2011: Hsieh et al, 2016: Lorente-Galdos et al, 2019: Xu et al, 2017). The relative consensus accorded to the small number of studies is that the source of this introgression is a now-extinct human population that split from the modern human lineage between 0.5 and 2 million years before the present. The time and place of the introgression event are not clear. For example, our own study found one likely introgression haplotype overlapping with the salivary MUC7 gene that is common to all African populations, suggesting that at least one introgression event occurred before the dispersal of ancestral populations in Africa (Xu et al., 2017). We estimated that this introgression occurred about 100,000 years before the present and that the source hominin population separated from anatomically modern humans about two million years before the present. Other studies using advanced genome-wide approaches have shown consistent evidence of such haplotypes across the genome (Durvasula and Sankararaman, 2018: Lorente-Galdos et al., 2019). A recent model-based approach suggests that population-specific introgression(s) may have occurred as little as 30,000 years before the present, affecting existing ancestral African populations (Hsieh et al., 2016). However, all of these dates are highly sensitive to demographic models, mutation rate estimates and recombination rate assumptions. Thus, a clearer, more definitive picture requires direct sequencing of the ancient African genomes of ancient hominins and anatomically older modern human remains from Africa. Regardless, evidence is accumulating that anatomically modern human genomes contain segments from an unknown hominin population that lived in Africa.
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